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Calling All Doctors ~ Consider Your Patient’s Unique Genetic Profile ~ 2,200,000 ADR’s occur Yearly ~ 700,000 Preventable ADRs are Hospitalized occur each Year ~ 100,000 Patients/Year have Fatal doses with Properly Prescribed FDA Drugs ~ ADRs have the FDA’s Attention ~ Match Your Patient’s DNA to the Best Drug Regimen based on Patient’s Unique Genetic Profile ~ DNA Screening is an Easy, Non-Invasive Buccal-Swabs ~ Takes the Risk out of Prescribing FDA Drugs ~ Genetic Tools give Major Reduction in ADR’s ๐Ÿ’Š๐Ÿ’Š๐Ÿ’Š๐Ÿ’Š๐Ÿ’Š๐Ÿ’Š๐Ÿ’Š

February 22, 2014

๐Ÿ’Š Advocating for your Patient’s health is very important, and Genetic Profiles are important tools for prescribing. Doctor’s are concerned about Drug Contradiction issues. Are your Patients taking one or more FDA approved Drugs plus a variety of Over-The-Counter Drugs? If so, consider Genelex Genetic Screening for all your PolyPharmacy, Cardiac, Geriatric, and Surgery Patients.

๐Ÿ’Š Calling All Doctors Consider Your Patient’s Unique Genetic Profile
๐Ÿ’Š 2,200,000 ADR’s occur Yearly
๐Ÿ’Š 700,000 Preventable ADRs are Hospitalized each Year
๐Ÿ’Š 100,000 Patients have Avoidable Fatal doses of Properly Prescribed FDA Drugs Yearly
๐Ÿ’Š ADRs have the focused Attention of the FDA
๐Ÿ’Š Match Your Patient’s DNA to the Best Drug Regimen based on your Patient’s Unique Genetic Profile
๐Ÿ’Š DNA Screening is Simple, Easy Non-Invasive collection with Buccal-Swabs
๐Ÿ’Š Genetic Profiling Takes the Risk of Prescribing FDA Drugs
๐Ÿ’Š Genetic Software Tools give Major Reduction in ADR’s, with real-time YouScript Drug Substitution tool

Genelex DNA Screening has high level of Interest by the FDA, Insurance Companies, Hospitals, Doctors and Malpractice Insurers because of the high level of significant ADR reactions:

๐Ÿ’Š 2.2 Million patients taking FDA Approved experiencing ARDs every Year
๐Ÿ’Š 700,000 Patients Yearly are Hospitalized
๐Ÿ’Š 180,000 Patients Yearly had fatalities
๐Ÿ’Š Most Insurance Companies Pay for Genelex DNA Screening
๐Ÿ’Š Medicare pays for Genelex DNA Screening
๐Ÿ’Š Genelex accepts whatever the Insurance Company pays
๐Ÿ’Š Genelex does not “Balance Bill” Patients for any unpaid balance after Insurance claim is processed
๐Ÿ’Š Malpractice Insurance Companies focusing on DNA Screening
๐Ÿ’Š FDA is Focusing on DNA Screening due to large number of ADRs
๐Ÿ’Š Drug induced ADR’s are the Leading Payout of Malpractice Claims
๐Ÿ’Š Genelex screens presently 2,700 FDA Approved Drugs, and cross-references 23,500 Pharmaceutical Notes and Bulletins

๐Ÿ’Š Genelex DNA testing assesses Drug:Drug Interaction and Drug:Gene Interaction, even for PolyPharmacy Patients, will be analyzed with incredible effectiveness. Before DNA screening, Prescribers could not be sure, how many Over-the-Counter Medications when combined with FDA Prescriptions will Interact with each other. Knowing a Patient’s unique Genetic Profile, removes the “guess-work” and gives the Prescriber factual Reports giving suggestions for alternative pharmaceuticals.

๐Ÿ’Š When Patients are taking several Properly Prescribed FDA approved Drugs, plus several Over-the-Counter formulations, Drug:Drug and Drug:Gene Interactions may cause Adverse Drug Reactions, sometimes causing the following

โค๏ธ Serious life-threatening Contradictions
โค๏ธ Rapid Heart Rate
โค๏ธ Abnormally High Blood Pressure
โค๏ธ Slow Pulse Rate
โค๏ธ Abnormally Low Blood Pressure
โค๏ธ Irregular Heart Beat Patterns
โค๏ธ Skin Rashes and Irritations
โค๏ธ Sub-dermal bleeding and bruising
โค๏ธ Breathing Difficulties
โค๏ธ Uncontrolled Coughing
โค๏ธ Lungs accumulating Fluids
โค๏ธ Blurred Vision and impairment
โค๏ธ Hearing Impairment
โค๏ธ Hearing Hyper-sensitivity to Sounds
โค๏ธ Severe Headaches
โค๏ธ Loss of Consciousness
โค๏ธ Dizziness and Attention Disorder

๐Ÿ’Š Genelex+YouScript DNA Testing Mitigates the Doctor’s “Guess-Work” of Prescribing Drugs ~ DNA Screening renders a Major Reduction of ADR’s ~ Patient’s DNA is Matched to the the Most Effective Drug Regimen based on the Patient’s unique DNA Genetic Profile.

๐Ÿ’Š Genelex has a host of Applications designed for the iPad, Laptops and Computers for access to Patient DNA screening and utilization of the YouScript software application. The patient-data is password protected with high level of security.

๐Ÿ’Š As Genelex’s DNA Laboratory Rep, I would be pleased to visit with all Doctors regardless of location in the USA.

๐Ÿ’Š Notice the Sample YouScript Patient ID Card. One week after the Doctor receives the the Patient’s unique Genetic Profile, YouScript mails to the Patient this Genetic Profile card, that any Doctor or Prescriber may refer to, to aid them in any future prescriptions the Patient may need.

๐Ÿ’Š The YouScript ID Card looks like a typical plastic “Credit Card” for Patient’s to keep their your wallet or purse, for easy use by Doctors, Prescribers, and Hospitals. Since a Patient’s DNA Phenotypes remain the same for their lifetime, this is valuable tool for the entire medical community. Pharmacists may also access this information, subject to patient approval, to aid in fulfilling prescriptions anywhere in the world.

๐Ÿ’Š Genelex+YouScript DNA Test Mitigates Doctor’s “Guess-Work.” DNA Screening Takes the Risk out of Prescribing Drugs. Results: A Major Reduction of ADR’s with Doctors who are using your Genetic Profile when Prescribing Drug regimens. 100,000 Patients/Year ingest Fatal doses of Properly Prescribed FDA Drugs. 700,000 Patients/Year are Hospitalized by Adverse Drug Reactions when taking Properly Prescribed FDA approved Drugs.

๐Ÿ’Š PolyPharmacy patients are those who are taking several medications. Sometimes a Doctor prescribes a medication to "off-set" or mitigate the adverse drug reaction of the "primary" prescribed medication.

๐Ÿ’Š Over 75% of ALL Patients have genetic variations that have the potential for Adverse Drug Reactions, (commonly called an ADR) for properly prescribed FDA approved drugs and over-the-counter medications.

๐Ÿ’Š Genelex DNA test is a non-invasive, simple cheek-swab procedure, where the Patient’s swabs (they are like Q-Tips with a 5″ stem) are packaged and FedEx’ed Overnight to the Genelex Lab. Within 2 to 3 days your DNA is classified into 4-metabolic rates, (for example: Rapid Metabolizer, Average, Intermediate or Poor Metabolizer).

๐Ÿ’Š Genelex+YouScript standard YouScript Panel, tests the Patient’s DNA for each of the Six Genotypes (specifically: CYP2D6, CYP2C9, CYP2C19, VKORC1, CYP3A4 and CYP3A5) that effect the Patient’s absorption of the Medication with the Patient’s unique DNA.

๐Ÿ’Š DNA Test results are called the Patient’s “Phenotypes” which are printed onto a Plastic Credit-Card sized Wallet Card, with the full report emailed to the Patient’s Doctor or Prescriber. The graphic is a Sample YouScript DNA Profile Report, showing Three important Drug:Gene Interactions accompanied by several Prescribing Suggestions.

๐Ÿ’Š Genelex DNA screening also assessed how the combination of Medications will be absorbed in a Patient’s Body with particular attention to potential ADR, adverse drug reactions, based on your unique Genetic Profile. DNA Test Report, the results will make suggestions to the Patient’s Prescriber/Doctor if a Drug or several Drugs are not best suited to the Patient’s particular Genotype.

๐Ÿ’Š Patients experiencing drug-sensitivity issues, Genelex DNA screening would offer important Drug:Drug and Drug:Gene contradictions. Patients should talk to their Doctors about Genelex-YouScript screening. I may be reached at 561-416-1100 and by eMail at

๐Ÿ’Š Patient’s Unique DNA Genotype Profile will not change in the Patient’s Lifetime, therefore this test is only performed once in a Patient’s lifetime.

๐Ÿ’Š At the risk of restating the obvious, its hard to imagine Prescribing without knowing the Patient’s incredibly valuable DNA Genetic Profile, so say thousands of Doctors who have adopted Genelex DNA screening, coupled with Genelex’s unique YouScript programing.

๐Ÿ’Š YouScript permits Prescribers to access the Patient’s Genetic Profile, where the Doctor may make pharmaceutical substitutions, in search of the best patient treatment results.

๐Ÿ’Š Genelex Lab’s YouScriptยฎ is a Revolutionary way of using Patients’ genetic profiles to help predict the medications that will be most efficacious for your Patient. Doctors know that every body metabolizes drugs differently.

๐Ÿ’Š Some Patients have trouble metabolizing specific drugs, which can mean the Drug may not reach proper therapeutic levels. Conversely, rapid metabolism can even lead to serious dosage-complications (an ADR). Finding the best match for the patient’s Medication regimen is critical. DNA screening is an effective prescribing tool.

๐Ÿ’Š YouScriptยฎ is a simple cheek-swab sample test, that analyzes the patient’s DNA and provides a comprehensive report so the physician can prescribe with confidence, rendering an effective treatment plan.

๐Ÿ’Š Patient’s health is the Doctor’s and Genelex Lab’s top priority. An open dialogue between the Patient and their Physician is a very important step in achieving this goal. The graphic below shows that DNA Screening shows Drug:Drug Interaction and Drug:Gene Interactions. DNA Screening gives specific Metabolism information specifically matched to the Drug treatment regimen recommended by your Doctor.

๐Ÿ’Š YouScript DNA genomic screening is available with a traditional "Prescription" from the doctor, and follow-up (including analysis of patient DNA test results) is conducted by the physician. Genelex has prepared some materials that will make it easy to talk to patients about what Genelex – YouScript is, and the benefit it provides for enhanced Drug treatment.

๐Ÿ’Š Approximately 85% of the Population have Genetic Variations that can effect the drug metabolism, significantly changing the a patient’s exposure to those drugs.

๐Ÿ’Š Genelex’s YouScript analyses 6-Key drug processing enzymes, namely the CYP2D6, CYP2C9, CYP2C19, VKORC1, CYP3A4 and CYP3A5.

๐Ÿ’Š Five Key Enzymes are relied upon by 50% of all commonly prescribed drugs, including drugs used for cardiovascular treatment, and pain medications, NSAIDs, the majority of all antidepressants, tamoxifen and the thousands of drugs that Genelex has in their data-base.

๐Ÿ’Š Having your specific metabolic-rate information helps your Doctor select the best combination of medications, most likely to succeed for a patient, in light of their specific genetic profile.

The Genelex YouScript DNA Test is a very Simple Process

๐Ÿ’Š (1) You meet with your Doctor as you usually do
๐Ÿ’Š (2) A prescription is written for the Genelex DNA Testing, Genelex submits the paperwork for billing the insurance company or MediCare, and there is no cost to the Doctor or the Doctors Office
๐Ÿ’Š (3) A simple cheek-swab is done to collect some of your DNA
๐Ÿ’Š (4) The Doctor provides a current list of all medications, herbals, and OTCs that you are taking, along with what the Doctor is currently recommending to be taken
๐Ÿ’Š (5) The list of medications and your test-swabs are packaged and Overnight FedEx’ed to Genelex Labs
๐Ÿ’Š (6) Five Days later the DNA Test results are delivered to your Doctor for his review
๐Ÿ’Š (7) Your Doctor examines the YouScript DNA Test results and formulates the best Drug Treatment plan, in light of your particular DNA metabolic rates for the various medications and combinations of all the medications
๐Ÿ’Š (8) Your Doctor than writes Prescriptions for the medications that are optimized and most efficacious for You.

๐Ÿ’Š The pages below are detailed information regarding a Patient’s phenotypes and the common drug interactions, for each of the Six Genotypes (specifically: CYP2D6, CYP2C9, CYP2C19, VKORC1, CYP3A4 and CYP3A5) that effect the Patient’s absorption of the Medication with the Patient’s unique genetic profile.

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PharmacoGenetic Screening: Having been trained as a BioChemist, I have an avid interest in PharmacoGenetics DNA Screening.

Last year 2.2 million patients taking prescribed FDA Approved Drugs have experienced an Adverse Drug Reaction (ADR); of those 770,000 experienced an ADR requiring Hospitalization, and 180,000 of those patients the ADR was fatal. Genomic DNA Testing done only once in your Lifetime, will give Physicians valuable information guiding against a patient being prescribed FDA Approved medications that do not suit your Genomic variants.

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